Neuroscience

Why stress doesn't always cause depression

Rats susceptible to anhedonia, a core symptom of depression, possess more serotonin neurons after being exposed to chronic stress, but the effect can be reversed through amygdala activation, according to new research in the ...

Psychology & Psychiatry

Genetic variation contributes to individual differences in pleasure

Differences in how our brains respond when we're anticipating a financial reward are due, in part, to genetic differences, according to research with identical and fraternal twins published in Psychological Science, a journal ...

Medications

New drug mimics benefits of ketamine for depression

A new small-molecule drug produced a rapid antidepressant response similar to that of ketamine when tested in mice, a new Yale-led study published April 16 in the Journal of Clinical Investigation shows.

Psychology & Psychiatry

People with anhedonia do experience pleasure, just not as often

Put bluntly, a hedonist is a bon vivant, or at the very least somebody whose highest priority is to enjoy life. If you suffer from anhedonia – the opposite of this – then you are in an unenviable position. During her ...

Psychology & Psychiatry

What is the best measure of depression severity in adolescents?

At present the key symptom for diagnosing major depressive disorder (MDD) in adolescents is irritability. However a new study has found that the severity of anhedonia (the inability to gain pleasure from experiences that ...

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