Diseases, Conditions, Syndromes

How can we get effective treatments for COVID-19?

Researchers across the world have responded rapidly to COVID-19—a new disease that we don't yet know how to treat. In the search to find safe and effective treatments, teams of scientists are looking into more than 200 ...

Medical research

New testing system predicts septic shock outcomes

More than 1.7 million Americans develop sepsis each year, and more than 270,000 die from it. The condition—which happens when the body has an extreme response to a bacterial or viral infection, causing a chain reaction ...

Medical research

Researchers publish new insights into COVID-19

Researchers at the Radboud University Medical Center seem to have found an essential mechanism in the disease process of COVID-19, which has so far been overlooked. If the insight is correct, it probably has important consequences ...

Medical research

Suspect cells' 'neighbor' implicated in colorectal cancer

Colorectal cancer kills more than 50,000 people a year in the United States alone, but scientists have struggled to find the exact mechanisms that trigger the growth of tumors in the intestine.

Arthritis & Rheumatism

A protein that controls inflammation

A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as rheumatoid arthritis, Crohn's ...

Medications

Popular painkiller ibuprofen affects liver enzymes in mice

The popular painkiller ibuprofen may have more significant effects on the liver than previously thought, according to new research from the University of California, Davis. The study in laboratory mice also shows marked differences ...

Medications

Choosing common pain relievers: It's complicated

About 29 million Americans use over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) to treat pain. Every year in the United States, NSAID use is attributed to approximately 100,000 hospitalizations and 17,000 deaths. ...

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Non-steroidal anti-inflammatory drug

Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs or NAIDs, are drugs with analgesic, antipyretic (lowering an elevated body temperature and relieving pain without impairing consciousness) and, in higher doses, with anti-inflammatory effects (reducing inflammation). The term "non-steroidal" is used to distinguish these drugs from steroids, which (among a broad range of other effects) have a similar eicosanoid-depressing, anti-inflammatory action. As analgesics, NSAIDs are unusual in that they are non-narcotic.

NSAIDs are sometimes also referred to as non-steroidal anti-inflammatory agents/analgesics (NSAIAs) or non-steroidal anti-inflammatory medicines (NSAIMs). The most prominent members of this group of drugs are aspirin, ibuprofen, and naproxen partly because they are available over-the-counter in many areas.

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