Cancer

Scientists alter 3-D genome using 'small molecules'

Researchers have discovered that the spatial organization of the genome can be altered using small molecule compounds which are considered as promising anti-cancer drugs. This work opens up the prospect of developing a new ...

Medical research

Cancer's SOS

RAS proteins regulate growth, survival and proliferation of cells in their active state. However, the uncontrolled activation of RAS causes approximately a third of all tumors and helps cancerous cells evade anti-cancer drugs. ...

Cancer

Researchers uncover key to greater efficacy in cancer treatment

Researchers from Mount Sinai and IBM have discovered a novel clue in explaining how cancer cells with identical genomes can respond differently to the same therapy. In a Nature Communications paper published today, researchers ...

Cancer

Balance of two enzymes linked to pancreatic cancer survival

Protein Kinase C (PKC) enzymes are crucial for a number of cellular activities, including cell survival, proliferation and migration—functions that must be carefully controlled lest cells get out of control and form a tumor. ...

Cancer

How prostate cancer becomes treatment resistant

The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant prostate ...

page 1 from 9