Autism spectrum disorders

Inflammation and autism—an important piece of the puzzle

Autism spectrum disorder has neither a distinct pathogenesis nor pharmaceutical treatment, yet evidence continues to mount demonstrating immune dysfunction and inflammation in specific brain regions of children diagnosed ...

Immunology

Gut throws cells overboard when chemical insults build up

A team of Duke researchers has discovered that cells lining the gut of zebrafish—and probably humans too—have a remarkable defense mechanism when faced with certain kinds of toxins: they hit the eject button.

Medical research

Study puts a new spin on ibuprofen's actions

Ibuprofen, naproxen, and related non-steroidal anti-inflammatory drugs (NSAIDs) – the subjects of years of study – still have some secrets to reveal about how they work.

Endocrinology & Metabolism

Acetylation: A timekeeper of glucocorticoid sensitivity

Cortisol, also commonly known as the stress hormone, belongs to the family of glucocorticoids. In addition to its physiological function, synthetic derivatives of cortisol are also used as anti-inflammatory drugs. In the ...

Diseases, Conditions, Syndromes

Tobacco smoke exposure linked to increased risk of tuberculosis

Researchers at Massachusetts General Hospital (MGH) have identified a potential mechanism by which tobacco smoking drives a type of white blood cell known as monocytes to the lung where they can increase the risk of active ...

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