Blood analysis predicts sepsis and organ failure in children
University of Queensland researchers have developed a method to predict if a child is likely to develop sepsis and go into organ failure.
Mar 26, 2024
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University of Queensland researchers have developed a method to predict if a child is likely to develop sepsis and go into organ failure.
Mar 26, 2024
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Compared to adults, newborns are highly susceptible to infections and these infections can cause serious health complications and even death.
Mar 15, 2024
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A person's age, sex and location are correlated with the chance that they have a bloodstream infection that is resistant to antibiotics, according to a new study published in PLOS Medicine by Gwenan Knight of the London School ...
Mar 14, 2024
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A new collaborative study discloses the discovery and application of a new therapeutic strategy to target the multidrug-resistant bacterium Salmonella enterica in vivo, with promising results. The results were published in ...
Mar 7, 2024
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A statistical model can accurately predict the risk of bloodstream infections in a subset of children with cancer, according to a study published in the Journal of Clinical Oncology.
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Salmonella is a bacterial infection that can cause fever, abdominal pain, nausea, vomiting or diarrhea. It can be transmitted from contaminated food, such as raw meat or eggs. But what you may not know is that your pets—and ...
2 hours ago
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Urinary tract infections (UTIs) caused by E. coli from aged care facilities show higher resistance to antibiotics compared to cases collected from hospitals and the wider community, find researchers from UNSW Sydney.
Mar 21, 2024
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H. pylori is one of the most common disease-causing bacteria. More than half of the world's population have the bacteria in their body; and while in Canada overall prevalence of H. pylori is between 20% and 30%, some groups—including ...
Mar 20, 2024
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New research indicates that antibiotics can effectively target bacteria in the gut that harbor the virus that causes COVID-19 and produce toxin-like peptides that contribute to COVID-19-related symptoms.
Mar 20, 2024
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The bacteria in our gut are believed to be involved in cancer of the large bowel. Exposure to antibiotics, which can affect gut bacteria, might do the same, according to a recent thesis from Umeå University.
Mar 19, 2024
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In common usage, an antibiotic (from the Ancient Greek: ἀντί – anti, "against", and βίος – bios, "life") is a substance or compound that kills bacteria or inhibits their growth. Antibiotics belong to the broader group of antimicrobial compounds, used to treat infections caused by microorganisms, including fungi and protozoa.
The term "antibiotic" was coined by Selman Waksman in 1942 to describe any substance produced by a microorganism that is antagonistic to the growth of other microorganisms in high dilution. This original definition excluded naturally occurring substances that kill bacteria but are not produced by microorganisms (such as gastric juice and hydrogen peroxide) and also excluded synthetic antibacterial compounds such as the sulfonamides. Many antibiotics are relatively small molecules with a molecular weight less than 2000 Da.[citations needed]
With advances in medicinal chemistry, most antibiotics are now semisynthetic—modified chemically from original compounds found in nature, as is the case with beta-lactams (which include the penicillins, produced by fungi in the genus Penicillium, the cephalosporins, and the carbapenems). Some antibiotics are still produced and isolated from living organisms, such as the aminoglycosides, and others have been created through purely synthetic means: the sulfonamides, the quinolones, and the oxazolidinones. In addition to this origin-based classification into natural, semisynthetic, and synthetic, antibiotics may be divided into two broad groups according to their effect on microorganisms: those that kill bacteria are bactericidal agents, while those that only impair bacterial growth are known as bacteriostatic agents.
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