Oncology & Cancer

Breast cancer resistance to CDK4/6 inhibitors arises in many ways

Breast cancer cells became resistant to therapeutics targeting CDK4/6, such as palbociclib (Ibrance), in multiple ways, and preclinical studies suggested different combinations of therapeutics may prevent and overcome the ...

Oncology & Cancer

Increased toxicity for many newly approved anticancer drugs

(HealthDay)—Newly approved anticancer drugs that do not have a specific molecular target on cancer cells are associated with increased toxicity and the accompanying costs of management, according to research published online ...

Medical research

Researchers find new class of highly potent antimalarial compounds

Despite renewed global efforts for eradication, malaria continues to exert devastating effects on human health. An estimated 220 million people are infected each year by malaria-causing Plasmodium parasites, which are transmitted ...

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