Neuroscience

Disinhibition plus instruction improve brain plasticity

(PhysOrg.com) -- The healthy brain has balance of excitatory and inhibitory signals that stimulate activity but also keep it under control. Some brain diseases, like autism and Down's syndrome, have too much inhibition, which ...

Psychology & Psychiatry

Molecular profiling of Ketamine's rapid antidepressant effect

One third of the patients with major depressive disorder suffer from treatment resistance and do not respond to commonly used antidepressants. Ketamine, a drug that works through a different mechanism, improves depressive ...

Medications

Neurosteroid antidepressants on horizon

More than 14 million Americans suffer from clinical depression, yet one in three doesn't experience relief from approved antidepressant drugs. A new treatment approach involving drugs called neurosteroids is on the horizon, ...

Psychology & Psychiatry

Why Big Pharma is not addressing the failure of antidepressants

Around a quarter of people experience depression at some point in their lives, two-thirds of whom are women. Each year more than 11m working days are lost in the UK to stress, depression or anxiety and there are more than ...

Psychology & Psychiatry

Blood test to personalize depression treatment for the first time

Scientists at King's College London have developed a blood test that accurately and reliably predicts whether depressed patients will respond to common antidepressants, which could herald a new era of personalised treatment ...

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