Oncology & Cancer

Improved cancer immunotherapies require radical CAR overhaul

CAR-T cell therapy is a new and revolutionary weapon against cancer: T cells are isolated from the patient's blood for genetic modification and then infused back into the patient to attack cancer cells. Researchers from the ...

Oncology & Cancer

CAR T cell therapy: Potential for considerable savings

Chimeric antigen receptor (CAR) T cell therapy is a new and in some cases highly effective form of immunotherapy to treat certain types of cancer of the blood and lymph system. This promising treatment comes at a cost, however: ...

Medical research

CAR T cells beyond cancer: Targeting senescence-related diseases

Chimeric antigen receptor (CAR) T cells have transformed the treatment of refractory blood cancers. These genetically engineered immune cells seek out and destroy cancer cells with precision. Now, scientists at Memorial Sloan ...

Oncology & Cancer

Infection risk up in month after CAR T-cell immunotherapy

(HealthDay)—For children and young adults receiving CD19 chimeric antigen receptor (CAR) T-cell infusion (CTI), infection rates increase in the first month after treatment and then decrease, according to a study published ...

Oncology & Cancer

CAR macrophages go beyond T cells to fight solid tumors

Chimeric antigen receptor (CAR) T cell therapy has been a game-changer for blood cancers but has faced challenges in targeting solid tumors. Now researchers from the Perelman School of Medicine at the University of Pennsylvania ...

Obstetrics & gynaecology

Designing an emergency stop switch for immunotherapies

Immunotherapy, unlike chemotherapy and radiotherapy, arms the body's immune system to attack cancer cells. In recent years, it has proven to be remarkably successful at treating leukemia, lymphoma and other liquid cancers, ...

Oncology & Cancer

Engineering the immune system to tackle glioblastoma

Each year, roughly 15,000 Americans are diagnosed with Glioblastoma Multiforme (GBM), the most common malignant primary brain tumor in adults, and also the most lethal. Surgery, radiation, and chemotherapy can help slow the ...

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