Neuroscience

Menopausal hormone changes linked to cognitive deficits

A new study led by UCLA neurologist Dr. Rhonda Voskuhl sheds light on the underlying mechanisms linking menopause to cognitive deficits and brain atrophy, revealing a crucial role for estrogen receptor beta (ERβ) in astrocytes. ...

Neuroscience

Ion channel linked to brain inflammation identified

Northwestern Medicine investigators have identified how a calcium channel in the nervous system contributes to brain inflammation, according to a study published in Nature Communications.

Neuroscience

The discovery of a new kind of cell shakes up neuroscience

A research team from University of Lausanne (UNIL) and the Wyss Center, has discovered a new type of cell essential for brain function. Hybrid in composition and function, in between the two types of brain cells known so ...

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Astrocyte

Astrocytes (etymology: astron gk. star, cyte gk. cell), also known collectively as astroglia, are characteristic star-shaped glial cells in the brain and spinal cord. They perform many functions, including biochemical support of endothelial cells that form the blood–brain barrier, provision of nutrients to the nervous tissue, maintenance of extracellular ion balance, and a role in the repair and scarring process of the brain and spinal cord following traumatic injuries.

Research since the mid-1990s has shown that astrocytes propagate intercellular Ca2+ waves over long distances in response to stimulation, and, similar to neurons, release transmitters (called gliotransmitters) in a Ca2+-dependent manner. Data suggest that astrocytes also signal to neurons through Ca2+-dependent release of glutamate. Such discoveries have made astrocytes an important area of research within the field of neuroscience.

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