A new study has found a molecule hailed as a potential drug candidate for Parkinson's disease is no longer an effective therapeutic option. The WEHI-led research has debunked over 10 years of research that suggested a specific ...
Jan 22, 2024
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Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter ...
Nov 1, 2023
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Deep inside our cells— each one complete with an identical set of genes— a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, vs. brain or muscle or skin cells.
Sep 26, 2023
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Using a state-of-the-art method, researchers at DZNE and the University of Texas have succeeded for the first time at unraveling the effects of autoimmune antibodies that are directed against the brain in detail at the atomic ...
Jul 8, 2022
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Scientists have, for the first time, revealed at the atomic level the structure of a protein that carries one of the body's most important neurotransmitters into neurons.
Jun 8, 2022
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Scientists at Memorial Sloan Kettering Cancer Center (MSK) have glimpsed never-before-seen details of the human androgen receptor—the protein inside of cells that responds to male-typical hormones like testosterone. Their ...
Apr 20, 2022
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As the effort to combat the SARS-CoV-2 virus began, among the most pressing questions were how to gauge its infectivity and get a better picture of those dynamics from the inside out. Answering them initially would bring ...
Mar 15, 2022
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New findings provide a better understanding of how the synthesis of dopamine is regulated in the brain. It may shed new light on the mechanism behind diseases such as Parkinson's.
Jan 12, 2022
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Chemokine receptors, located at the surface of many immune cells, play an important role in cell function. Chemokines are small proteins that bind to these receptors and control the movement and behavior of white blood cells.
Jun 16, 2021
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Researchers at Umeå University in Sweden have for the first time at the atomic level succeeded in mapping what a virus looks like that causes diarrhea and annually kills about 50,000 children in the world. The discovery ...
Jan 11, 2021
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In quantum mechanics, perturbation theory is a set of approximation schemes directly related to mathematical perturbation for describing a complicated quantum system in terms of a simpler one. The idea is to start with a simple system for which a mathematical solution is known, and add an additional "perturbing" Hamiltonian representing a weak disturbance to the system. If the disturbance is not too large, the various physical quantities associated with the perturbed system (e.g. its energy levels and eigenstates) can, from considerations of continuity, be expressed as 'corrections' to those of the simple system. These corrections, being 'small' compared to the size of the quantities themselves, can be calculated using approximate methods such as asymptotic series. We can therefore study the complicated system based on our knowledge of the simpler one.
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