Diseases, Conditions, Syndromes

Scientists discover new mechanism associated with severe COVID-19

Researchers at the University of São Paulo (USP) in Brazil have found that severe COVID-19 is associated with an imbalance in an important immune system signaling pathway. The discovery helps explain at the molecular level ...

Diseases, Conditions, Syndromes

New mitochondrial disease identified in identical twins

In a set of identical twins, investigators led by researchers at Massachusetts General Hospital (MGH) and Children's Hospital Philadelphia (CHOP) have identified a mitochondrial disease not previously reported.

Oncology & Cancer

Scientists create nanoparticle that helps fight solid tumors

Researchers from Wake Forest University School of Medicine have discovered a possible new approach in treating solid tumors through the creation of a novel nanoparticle. Solid tumors are found in cancers such as breast, head ...

Biomedical technology

Sensor monitors disease severity by rapidly measuring lactate levels

Scientists have developed a prototype sensor that could help doctors rapidly measure adenosine triphosphate (ATP) and lactate levels in blood samples from patients, aiding in the rapid assessment of the severity of some diseases.

Immunology

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system. An imbalance of microbial metabolites has been implicated ...

Genetics

A 'pump' gene's surprising role in early brain formation

In polymicrogyria, the cortex of the brain has many irregular, small folds (gyria) and disorganization of its layers. Many affected children have severe developmental delay, intellectual disabilities, and epilepsy, and many ...

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