Neuroscience

Model explores how statins alter multiple sclerosis outcomes

(HealthDay)—Simvastatin's beneficial effects on clinical outcomes and brain atrophy in patients with multiple sclerosis (MS) are largely independent of cholesterol levels, according to a post hoc study published in the ...

Medications

FDA approves $2M medicine, most expensive ever

U.S. regulators have approved the most expensive medicine ever, for a rare disorder that destroys a baby's muscle control and kills nearly all of those with the most common type of the disease within a couple of years.

Medical research

Spinal organoids mimic neurodegenerative disease

'Organoids' that mimic the developing spinal cord could assist research and drug development for neurodegenerative diseases such as spinal muscular atrophy and amyotrophic lateral sclerosis.

Alzheimer's disease & dementia

Does diabetes damage brain health?

(HealthDay)—Diabetes has been tied to a number of complications such as kidney disease, but new research has found that older people with type 2 diabetes can also have more difficulties with thinking and memory.

Neuroscience

Memory tests predict brain atrophy and Alzheimer's disease

Mild cognitive impairment is a heterogeneous condition; it may may be reversible or permanent. but it is also associated with a higher risk of dementia, Alzheimer's disease in particular. Mild cognitive impairment refers ...

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Atrophy

Atrophy is the partial or complete wasting away of a part of the body. Causes of atrophy include poor nourishment, poor circulation, loss of hormonal support, loss of nerve supply to the target organ, disuse or lack of exercise or disease intrinsic to the tissue itself. Hormonal and nerve inputs that maintain an organ or body part are referred to as trophic.

Atrophy is a general physiological process of reabsorption and breakdown of tissues, involving apoptosis on a cellular level. When it occurs as a result of disease or loss of trophic support due to other disease, it is termed pathological atrophy, although it can be a part of normal body development and homeostasis as well.

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