Interstitial nephritis, a common cause of kidney failure, has a complex and largely unknown pathogenesis. In a new published paper in The Journal of the American Society of Nephrology (JASN), a team of researchers led from ...
Mar 18, 2016
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β cells in pancreatic islets are responsible for producing insulin, which is essential to regulate blood glucose homeostasis. In type 1 diabetes, pancreatic β cells are destroyed due to an autoimmune attack, whereas in ...
Mar 17, 2016
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Investigators at Montreal's Lady Davis Institute at the Jewish General Hospital and McGill University Health Centre have announced the start of a landmark clinical study aimed at restoring normal insulin secretion in people ...
Nov 25, 2015
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(HealthDay)—Like many other animals, man's best friend isn't immune to developing diabetes. But new research suggests that while the disease in dogs looks similar to type 1 diabetes in people, there are some significant ...
Sep 17, 2015
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(MedicalXpress)—Originating in the thymus, the autoimmune regulator (Aire) protein controls a key mechanism that prevents the immune system from attacking the body itself. Individual T cells attack different substances; ...
A new study has found a strong link between prolonged work at the World Trade Center (WTC) site following the terrorist attacks of September 11, 2001 and the development of various autoimmune diseases including arthritis ...
Mar 16, 2015
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High blood pressure is a major risk factor for heart attack, stroke, chronic heart failure, and kidney disease. Inflammation is thought to promote the development of high blood pressure, though it is not clear what triggers ...
Sep 17, 2014
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The code for every gene includes a message at the end of it that signals the translation machinery to stop. Some diseases, such as cystic fibrosis and Duchenne muscular dystrophy, can result from mutations that insert this ...
Mar 31, 2014
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St. Jude Children's Research Hospital scientists have discovered a way to target the immune system to shrink or eliminate tumors in mice without causing autoimmune problems. Researchers also found evidence that the same mechanism ...
Aug 4, 2013
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Scientists have uncovered the mechanism that controls whether cells that are able to suppress immune responses live or die.
Jul 14, 2013
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