Researchers at National Jewish Health have identified a trigger for autoimmune diseases such as lupus, Crohn's disease and multiple sclerosis. The findings, published in the April 2017 issue of Journal of Clinical Investigation, ...
May 11, 2017
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Autoimmune diseases (AD) such as rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease and psoriasis, are a leading cause of morbidity and mortality as people age. Few effective treatments are available ...
Jan 26, 2022
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Salk scientists have uncovered an unexpected molecular target of a common treatment for alopecia, a condition in which a person's immune system attacks their own hair follicles, causing hair loss. The findings, published ...
Jun 23, 2022
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Greg Widseth didn't know what hit him. The lawyer felt fine as he coached his son's ninth-grade basketball workout last March. He remembers smiling at a young woman as he left the building.
Mar 31, 2015
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In a world first, researchers from The Australian National University (ANU) have shown previously ignored rare genetic mutations are a major cause of lupus.
May 17, 2019
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Researchers at the University of Colorado Anschutz Medical Campus have discovered that having one kind of autoimmune disease can lead to another.
Jan 4, 2022
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Fasting regimens have gained public and scientific interest in recent years, but fasting shouldn't be dismissed as a fad. In a study published in Cell, Mount Sinai researchers found that fasting reduces inflammation and improves ...
Aug 22, 2019
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Women with breast implants mostly only had to worry about leaks, but a large-scale Israeli study performed in collaboration with researchers from the University of Alberta confirmed almost one in four implantation patients ...
Nov 7, 2018
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Surgical mesh implants, often used for hernia or gynecological repair, may be the reason so many patients report symptoms of an autoimmune disorder, according to a University of Alberta rheumatologist.
Jul 31, 2018
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Sjögren's syndrome hit the headlines when US tennis player Venus Williams declared she was suffering from it.
Apr 30, 2019
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Autoimmunity is the failure of an organism to recognize its own constituent parts as self, which allows an immune response against its own cells and tissues. Any disease that results from such an aberrant immune response is termed an autoimmune disease. Autoimmunity is often caused by a lack of germ development of a target body and as such the immune response acts against its own cells and tissues. Prominent examples include Coeliac disease, diabetes mellitus type 1 (IDDM), systemic lupus erythematosus (SLE), Sjögren's syndrome, Churg-Strauss Syndrome, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, rheumatoid arthritis (RA), lupus and allergies. Autoimmune diseases are very often treated with steroids.
The misconception that an individual's immune system is totally incapable of recognizing self antigens is not new. Paul Ehrlich, at the beginning of the twentieth century, proposed the concept of horror autotoxicus, wherein a 'normal' body does not mount an immune response against its own tissues. Thus, any autoimmune response was perceived to be abnormal and postulated to be connected with human disease. Now, it is accepted that autoimmune responses are an integral part of vertebrate immune systems (sometimes termed 'natural autoimmunity'), normally prevented from causing disease by the phenomenon of immunological tolerance to self-antigens. Autoimmunity should not be confused with alloimmunity.
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