Medications

A new drug candidate can shrink kidney cysts

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function. The disease affects more than 12 million people worldwide, ...

Genetics

Researchers develop novel mouse model for A-T mutations

The Lundquist Institute's investigators have developed a novel mouse model that displays the most comprehensive set of A-T symptoms which provides for the very first time a resource to not only clarify the mechanisms of this ...

Genetics

Study: Genetic kidney disorder reversible in preclinical models

Autosomal dominant polycystic kidney disease (ADPKD), a genetic disorder, causes fluid-filled cysts to develop on the kidneys, which can impair their function. As part of the growth of cysts, the kidneys develop inflammation ...

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