Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function. The disease affects more than 12 million people worldwide, ...
Jan 22, 2024
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Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal genetic disease—about a half million people in the United States alone suffer from the condition. There is no cure, but new research ...
Apr 3, 2023
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Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern ...
Sep 16, 2022
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In a new study in Cell Stem Cell, scientists from the USC laboratory of Andy McMahon generated simple kidney-like structures called organoids and used them to identify potential drugs to treat adult-onset polycystic kidney ...
Jul 7, 2022
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Autosomal dominant polycystic kidney disease (ADPKD), a genetic disorder, causes fluid-filled cysts to develop on the kidneys, which can impair their function. As part of the growth of cysts, the kidneys develop inflammation ...
Oct 13, 2021
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Scientists from the University of Sheffield are part of an international collaboration to develop a new class of drugs to treat a common genetic kidney disease which is a major cause of kidney failure.
Jun 18, 2019
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Kidney doctors and clinical scientists at Sheffield Teaching Hospitals NHS Foundation Trust are using artificial intelligence (AI) to better predict when a person's kidneys might fail.
Mar 4, 2024
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A new study has shown that ketosis—a state in which the body primarily uses dietary fats as energy sources—may have positive effects on kidney function in people affected by hereditary polycystic kidney disease.
Nov 8, 2022
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Most families with autosomal dominant polycystic kidney disease (ADPKD) possess a genetic mutation in PKD1 that impacts the protein polycystin-1 (PC1).
Oct 26, 2022
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Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic condition that can lead to kidney failure and that has no cure. Recent research published in JASN uncovers an over-looked mechanism that likely contributes ...
Jul 12, 2022
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