Medical research

Cell signaling pathway linked to obesity, Type 2 diabetes

(Medical Xpress)—A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery ...

Medical research

Team finds on-off switch to burning stored fat

Scientists this week reported that a molecular pathway called mTORC1 controls the conversion of unhealthy white fat into beige fat, an appealing target for increasing energy expenditure and reducing obesity. The team, led ...

Immunology

Activating the immune system could treat obesity and diabetes

Obesity is a worldwide epidemic that is causing alarming rates of diabetes and cardiovascular disease, but currently there is a lack of effective drug treatments. Two unrelated studies published by Cell Press June 5th in ...

Immunology

Immune system molecules may promote weight loss, study finds

The calorie-burning triggered by cold temperatures can be achieved biochemically – without the chill – raising hopes for a weight-loss strategy focused on the immune system rather than the brain, according to a new study ...

Medical research

'Beige' cells key to healthy fat

"Beige fat" cells found in healthy subcutaneous fat in mice play a critical role in protecting the body from the disease risks of obesity, report researchers at Dana-Farber Cancer Institute, who say their study findings may ...

Medical research

How 'beige' fat makes the pounds melt away

Researchers from the University of Bonn and the Max Planck Institute of Biochemistry in Martinsried have decoded a signal path that could boost the burning of body fat. Mice that are missing a signal switch called VASP are ...

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