Oncology & Cancer
Doctors identify molecular cause of eye cancer
Researchers have identified a molecular mechanism that drives the progression of uveal melanoma (UM), an often lethal eye cancer in adults.
Sep 13, 2021
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News tagged with biological mechanisms
Genetics
'Noisy' gene expression plays key role in development and may help improve stem cell therapies
To speed up a chemical reaction, a chemist might place the reactants over a Bunsen burner. Adding heat increases the degree of random movements and collisions of particles, accelerating the reaction.
Jul 23, 2021
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Oncology & Cancer
Carcinogen-exposed cells provide clues in fighting treatment-resistant cancers
Researchers from Massachusetts General Hospital (MGH) have discovered a biological mechanism that transforms cells exposed to carcinogens from environmental factors like smoking and ultraviolet light into immunogenic cells ...
Jun 18, 2021
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Oncology & Cancer
Predicting resistance to anticancer drugs
Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails. Understanding this 'choice' by the cancer cells may ...
Jun 17, 2021
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Immunology
Aging impairs anti-tumor T-cell response via mitochondria dysfunction
MUSC Hollings Cancer Center researchers are finding solutions to the aging-related changes that reduce anti-cancer immunity. Besim Ogretmen, Ph.D., and colleagues found a novel link between aging, metabolism and anti-cancer ...
Jun 3, 2021
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Oncology & Cancer
Identifying new targeted therapy approaches for leukemia
A team of Northwestern Medicine scientists led by Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, has identified the molecular mechanisms of ASXL1 mutations ...
May 27, 2021
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Immunology
Maintaining self-control: The careful balance of the immune system
Autoimmune diseases occur when an individual's immune system fights their own body as if it was a foreign invader. However, in healthy people, these responses are prevented by a process known as immune tolerance. Many complex ...
May 19, 2021
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Medical research
Transporter imbalance implicated in schizophrenia
Alterations in the balance of two chloride ion transporters may be responsible for cognitive deficits in schizophrenia, according to a Northwestern Medicine study published in Science Advances.
Apr 27, 2021
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Oncology & Cancer
The enemy within: Understanding the mechanisms of r-chop resistance in b-cell lymphoma
White blood cells or lymphocytes are the soldiers of our immune system that patrol the body via the lymphatic system. While their primary role is to protect the body by scavenging invaders, they can sometimes go rogue and ...
Mar 2, 2021
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Gerontology & Geriatrics
New research identifies biological causes of muscle weakness in later life
A new largescale genetic analysis has found biological mechanisms that contribute to making people more susceptible to muscle weakness in later life, finding that diseases such as osteoarthritis and diabetes may play a large ...
Feb 11, 2021
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