Medical research

Biosensor barcodes identify, detail 'chatting' among cancer cells

Ever since the first barcode appeared on a pack of chewing gum in 1974, the now-ubiquitous system has enabled manufacturers, retailers and consumers to quickly and effectively identify, characterize, locate and track products ...

Oncology & Cancer

Using light to monitor cancer

Researchers at EPFL have developed a technology based on nanophotonics and data science to detect and monitor cancer biomarkers at an early stage. Their research is published in Nature Communications.

Oncology & Cancer

New biosensor developed to aid early diagnosis of breast cancer

A team of Spanish researchers have developed, at the laboratory level, a prototype of a new biosensor to help detect breast cancer in its earliest stages. One of the team coordinators has been Ramón Martínez Máñez, a ...

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A biosensor is a device for the detection of an analyte that combines a biological component with a physicochemical detector component.

It consists of 3 parts:

The most widespread example of a commercial biosensor is the blood glucose biosensor, which uses the enzyme glucose oxidase to break blood glucose down. In doing so it first oxidizes glucose and uses two electrons to reduce the FAD (a component of the enzyme) to FADH2. This in turn is oxidized by the electrode (accepting two electrons from the electrode) in a number of steps. The resulting current is a measure of the concentration of glucose. In this case, the electrode is the transducer and the enzyme is the biologically active component.

Recently, arrays of many different detector molecules have been applied in so called electronic nose devices, where the pattern of response from the detectors is used to fingerprint a substance. Current commercial electronic noses, however, do not use biological elements.

A canary in a cage, as used by miners to warn of gas could be considered a biosensor. Many of today's biosensor applications are similar, in that they use organisms which respond to toxic substances at a much lower level than us to warn us of their presence. Such devices can be used in environmental monitoring, trace gas detection and in water treatment facilities.

This text uses material from Wikipedia, licensed under CC BY-SA