Oncology & Cancer

Mutations in donors' stem cells may cause problems for cancer patients

A stem cell transplant—also called a bone marrow transplant—is a common treatment for blood cancers, such as acute myeloid leukemia (AML). Such treatment can cure blood cancers but also can lead to life-threatening complications, ...

Medical research

The 'supercells' that cured an infant's grave genetic illness

When a person's immune system is impaired by a genetic disease, a bone-marrow transplant can be a powerful therapeutic tool, but with a major downside: during the first few months the recipient's defenses against viruses ...

Medical research

Making blood on demand: How far have we come?

The reconstitution of the blood system in humans holds great therapeutic potential to treat many disorders, like blood cancers, sickle-cell anemia and others. Successful reconstitution requires the transplantation and engraftment ...