Alzheimer's disease & dementia

Sugar's 'tipping point' link to Alzheimer's disease revealed

For the first time a "tipping point" molecular link between the blood sugar glucose and Alzheimer's disease has been established by scientists, who have shown that excess glucose damages a vital enzyme involved with inflammation ...

Health

Need to control blood sugar? There's a drink for that

With more people with diabetes and pre-diabetes looking for strategies to help control blood sugar, new research from UBC's Okanagan campus suggests that ketone monoester drinks—a popular new food supplement—may help ...

Neuroscience

How gut bacteria negatively influences blood sugar levels

Millions of people around the world experience serious blood sugar problems which can cause diabetes, but a world first study is revealing how gut bacteria impact the normally feel good hormone serotonin to negatively influence ...

Diabetes

New theory on how insulin resistance, metabolic disease begin

Does eating too much sugar cause type 2 diabetes? The answer may not be simple, but a study published Sept. 26 in the Journal of Clinical Investigation adds to growing research linking excessive sugar consumption—specifically ...

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Blood sugar

Blood sugar concentration, or glucose level, refers to the amount of glucose present in the blood of a human or animal. Normally, in mammals the blood glucose level is maintained at a reference range between about 3.6 and 5.8 mM (mmol/l). It is tightly regulated as a part of metabolic homeostasis.

Mean normal blood glucose levels in humans are about 90 mg/100ml, equivalent to 5mM (mmol/l) (since the molecular weight of glucose, C6H12O6, is about 180 g/mol). The total amount of glucose normally in circulating human blood is therefore about 3.3 to 7g (assuming an ordinary adult blood volume of 5 litres, plausible for an average adult male). Glucose levels rise after meals for an hour or two by a few grams and are usually lowest in the morning, before the first meal of the day. Transported via the bloodstream from the intestines or liver to body cells, Glucose is the primary source of energy for body's cells, fats and oils (ie, lipids) being primarily a compact energy store.

Failure to maintain blood glucose in the normal range leads to conditions of persistently high (hyperglycemia) or low (hypoglycemia) blood sugar. Diabetes mellitus, characterized by persistent hyperglycemia from any of several causes, is the most prominent disease related to failure of blood sugar regulation.

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