Medications

Dual delivery of BMP2 and IGF1 promotes cranial bone defect healing

A new dual delivery system designed to sequentially release BMP2 and IGF1 in microparticles in an injectable hydrogel successfully healed an 8-mm cranial defect in rats. The study design and results are reported in the peer-reviewed ...

Genetics

Bioprinting for bone repair improved with gene therapy

Given enough time and energy, the body will heal, but when doctors or engineers intervene, the processes do not always proceed as planned because chemicals that control and facilitate the healing process are missing. Now, ...

Biomedical technology

Making bone growth transparent

As our bodies grow throughout childhood and puberty, our final height and the shape of our skeleton are largely determined by growth plates—areas of new growth at both ends of the long bones, such as those in the arms, ...

Biomedical technology

Implant shows extreme promise for regenerating bone

Its powers may not rival Wolverine's, but a regenerative implant engineered by researchers at the University of Nebraska Medical Center and University of Nebraska–Lincoln could help repair bone-deep damage following physical ...

Immunology

Improving bone marrow transplants in mice to help fight disease

To study the immune system in human health and disease, scientists commonly use the genetic manipulation of mouse hematopoietic stem and progenitor cells (HSPCs) as a powerful model system. These studies have been extremely ...

Medical research

Bioceramic implant induces cranial regrowth

A bioceramic implant has proved to stimulate regeneration of natural skull bone, so that even large cranial defects can be repaired in a way that has not been possible before. The research, led from the University of Gothenburg, ...

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Ossification

Ossification is a medical term that is synonymous with bone tissue formation. Endochondral ossification and intramembranous ossification are two processes resulting in the formation of normal, healthy bone tissue. Heterotopic ossification is a process resulting in the formation of bone tissue, that is often atypical, at an extraskeletal location. Calcification is a medical term that is often confused with ossification. Calcification is synonymous with the formation of calcium-based salts and crystals within cells and tissue. Calcification is a process that occurs during ossification, but not vice versa.

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