Medical research

High blood sugar levels 'reprogram' stem cells

High levels of glucose in the blood "reprogrames" stem cells, leading to a lasting increase in the risk of developing dangerous atherosclerosis, according to research funded by the British Heart Foundation published today ...

Oncology & Cancer

Sensing 'junk' RNA after chemotherapy enhances blood regeneration

Chemotherapy is widely used to treat cancer patients. During the treatment, chemotherapeutic agents affect various biochemical processes to kill or reduce the growth of cancer cells, which divide uncontrollably in patients. ...

Surgery

Mayo Clinic: Why bone marrow donor diversity is needed

Bone marrow transplants are procedures that infuse healthy blood stem cells into your body to replace damaged or diseased bone marrow. Just like people in need of solid organ transplants, such as hearts or kidneys, people ...

Oncology & Cancer

Blood stem cells make brain tumors more aggressive

For the first time, scientists from the German Cancer Consortium (DKTK) partner site in Essen/Düsseldorf have discovered stem cells of the hematopoietic system in glioblastomas, the most aggressive form of brain tumor. These ...

Immunology

Improving bone marrow transplants in mice to help fight disease

To study the immune system in human health and disease, scientists commonly use the genetic manipulation of mouse hematopoietic stem and progenitor cells (HSPCs) as a powerful model system. These studies have been extremely ...

Medical research

Studies reveal skull as unexpected source of brain immunity

The immune system is the brain's best frenemy. It protects the brain from infection and helps injured tissues heal, but it also causes autoimmune diseases and creates inflammation that drives neurodegeneration.

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