Immunology

Researchers find elusive source of most abundant immune cell

Neutrophils—short-lived, highly mobile and versatile—outnumber all other immune cells circulating through the blood stream. Yet, despite the cells' abundance, the progenitor cell that only gives rise to neutrophils had ...

Oncology & Cancer

Modifying the major model of a modern major mouse model

If a new anti-cancer drug shows promise in a Petri dish, often the next step is to test the drug's effect in mice. This system tends to work well with drugs that directly target cancer, but breaks down with immunotherapies. ...

Oncology & Cancer

Discovery could lead to better treatment for leukemia

Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About one-third of leukemia patients possess ...

Oncology & Cancer

Researchers map 'family trees' of acute myeloid leukemia

For the first time, a team of international researchers has mapped the family trees of cancer cells in acute myeloid leukaemia (AML) to understand how this blood cancer responds to a new drug, enasidenib. The work also explains ...

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