Medical research

Brain organoids develop optic cups that respond to light

Human induced pluripotent stem cells (iPSCs) can be used to generate brain organoids containing an eye structure called the optic cup, according to a study published August 17 in the journal Cell Stem Cell. The organoids ...

Neuroscience

Scientists reveal two paths to autism in the developing brain

Two distinct neurodevelopmental abnormalities that arise just weeks after the start of brain development have been associated with the emergence of autism spectrum disorder, according to a new Yale-led study in which researchers ...

Neuroscience

Miniature brain models help our understanding of autism

To better understand the causes of autism spectrum disorders (ASD), it is crucial to look at what is happening in the brain during development. The closest we come to observing human brains this early is by using organoids—miniature ...

Medical research

Mounting brain organoid research reignites ethical debate

As research involving the transplantation of human "mini-brains"—known as brain organoids—into animals to study disease continues to expand, so do the ethical debates around the practice. One concern is the possibility, ...

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