Oncology & Cancer

New drug targets for lethal brain cancer discovered

More than 200 genes with novel and known roles in glioblastoma—the most aggressive type of brain cancer—offer promising new drug targets. Researchers from the Wellcome Sanger Institute, Addenbrooke's Hospital and their ...

Neuroscience

The discovery of a 'negative regulator' in the brain

The brain has an uncanny ability to enhance or reduce communication between brain cells. Whether or not communication is fast or slow changes the brain's overall function. Understanding how these cells communicate within ...

Neuroscience

Estrogen's role in the sex differences of alcohol abuse

Fluctuating estrogen levels may make alcohol more rewarding to female mice, according to new research in JNeurosci. Untangling the involved signaling pathways could unveil sex-based treatments for alcohol use disorders.

Neuroscience

How serotonin balances communication within the brain

The brain is steadily engaged in thought. These internal communications are also usually bombarded with external sensory events. Hence, the impact of the two neuronal processes need to be permanently fine-tuned to avoid their ...

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