Oncology & Cancer

The long and short of CDK12

Mutations in the BRCA1 and BRCA2 genes pose a serious risk for breast and ovarian cancer because they endanger the genomic stability of a cell by interfering with homologous recombination repair (HR), a key mechanism for ...

Oncology & Cancer

Scientists discover gene linked to breast and ovarian cancer

(Medical Xpress)—A team of researchers led by the Institute of Cancer Research, London, have found that rare mutations in a gene called PPM1D are linked to an increased risk of breast and ovarian cancer. The mutations are ...

Oncology & Cancer

New recommendations on genetic testing for prostate cancer

Prostate cancer is a leading cause of death from cancer in the US and especially in the Philadelphia region. Consistently, Philadelphia has outpaced the state of PA and the nation in diagnoses and death from prostate cancer. ...

Oncology & Cancer

Study finds new member of the breast-cancer gene network

The infamous BRCA genes do not act alone in causing cancer; there is a molecular syndicate at work preventing the way cells normally repair breaks in DNA that is at the root of breast cancer. But finding all of the BRCA molecular ...

Oncology & Cancer

New breast cancer genetic mutation found in Chinese population

A genetic mutation that appears to be associated with a high breast cancer risk has been identified by researchers from Hong Kong. It is likely to be important enough to be included in genetic screening for people of Chinese ...

Oncology & Cancer

Ovarian cancer patients survive longer with BRCA2 mutated in tumors

Women with high-grade ovarian cancer live longer and respond better to platinum-based chemotherapy when their tumors have BRCA2 genetic mutations, researchers at The University of Texas MD Anderson Cancer Center and the Institute ...

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