The treatment of breast cancer abounding in the protein HER2 was revolutionized with the introduction of drugs like trastuzumab (Herceptin) that target the protein. When researchers discovered that breast cancers with lower ...
Jun 24, 2022
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Immunotherapies have revolutionized treatment for people with a variety of cancers. But when given to those with triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, less than 20% respond.
Apr 13, 2020
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Scientists from Brigham and Women's Hospital and Dana-Farber Cancer Institute and their colleagues have found a genetic marker that predicts which aggressive "triple negative" breast cancers and certain ovarian cancers will ...
Mar 22, 2012
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"Clean margins" are a goal of cancer excision surgery. If even a small piece of cancerous tissue is left behind, it increases the likelihood of a local recurrence and spread of the disease, possibly reducing overall survival ...
Jun 30, 2020
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Every parent knows the maxim "feed a cold, starve a fever." In cancer, however, exactly how to feed or starve a tumor has not been easy to determine.
Jul 16, 2015
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CAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood cancers, may enhance the effectiveness of surgery for solid tumors, according to a preclinical study from researchers in the ...
Jan 11, 2023
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The trefoil factor 3 (TFF3) protein protects and maintains the integrity of the epithelial surface in the normal breast. New research has found that while TFF3 protein expression is higher in well-differentiated low grade ...
Feb 16, 2012
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Using human breast cancer cells and the protein that causes fireflies to glow, a Johns Hopkins team has shed light on why some breast cancer cells become resistant to the anticancer effects of the drug tamoxifen. The key ...
Jul 27, 2011
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A study has revealed that tumors can evade the immune system by telling immune cells to produce immunosuppressive steroids. Researchers from the Wellcome Sanger Institute, Department of Pathology, University of Cambridge, ...
Jul 30, 2020
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Exercise training may slow tumor growth and improve outcomes for females with breast cancer—especially those treated with immunotherapy drugs—by stimulating naturally occurring immune mechanisms, researchers at Massachusetts ...
Apr 12, 2021
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