Johns Hopkins scientists report they have developed an antibody against a specific cellular gateway that suppresses lung tumor cell growth and breast cancer metastasis in transplanted tumor experiments in mice, according ...
Mar 16, 2016
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The uncontrolled growth of cancer cells arises from their ability to hijack the cell's normal growth program and checkpoints. Usually after therapy, a second cancer-signaling pathway will open after the primary one shuts ...
Oct 27, 2014
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Researchers from Indiana University School of Medicine are discovering new ways to find out how effective a drug might be against cancer. Their findings are detailed in a new paper published by Science Advances.
Jan 17, 2022
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Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the ...
Apr 11, 2013
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A unique antibody drug conjugate (ADC), which delivers a high dose of a cancer-killing drug to tumor cells through a targeted antibody, has been found in a global phase 3 clinical study to nearly double the survival time ...
Apr 21, 2021
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Mutations that are found in stem cells could be causing some breast cancers to develop and may be the reason the disease recurs. These abnormal cells are likely controlling cell functions in the tumor and, given they are ...
Aug 16, 2011
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The connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the site of a wound, instigating an inflammatory response that mends damaged tissue.
Dec 19, 2019
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Cancer cells have various tricks up their metaphorical sleeves to survive in the face of chemotherapy, radiotherapy and other cancer treatments. Now researchers at Mayo have decoded one of those tricks using cell lines and ...
Apr 30, 2019
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A new study published in Science Translational Medicine has found that in women with BRCA gene mutations, having a high body mass index (BMI) is linked to more DNA damage in breast cells. Specifically, the study discovered ...
When cancer cells break away from a primary tumor and migrate to other organs, this is called "metastatic cancer." The organs affected by these metastases, however, depend in part on their tissue of origin. In the case of ...
Apr 21, 2022
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