Medical research

Scientists unveil how general anesthesia works

Hailed as one of the most important medical advances, the discovery of general anesthetics—compounds that induce unconsciousness, prevent control of movement and block pain—helped transform dangerous and traumatic operations ...

Cardiology

Widely used blood pressure drugs might put heart at risk

Drugs based on a molecule called dihydropyridine are commonly prescribed by doctors to treat high blood pressure and angina, a chest pain caused by reduced blood flow to the heart. However, there's a chance that these same ...

Medical research

A new pathway for an anti-aging drug

In 1972, Easter Island, called Rapa Nui, famous for its moai statues, offered a new wonder: the discovery of the drug rapamycin.

Alzheimer's disease & dementia

New biomarker for Alzheimer's disease found via CRISPR technique

The objective of the research, undertaken in the laboratories of the IBPM, is to develop a model for studying Alzheimer's disease (AD) of sporadic origin—in other words, AD that is not due to a hereditary genetic mutation. ...

Neuroscience

A docking site per calcium channel cluster

A study co-led by Ryuichi Shigemoto and Alain Marty concludes that a single docking site may use a single cluster of calcium channels, and that both the number of docking sites and the number of calcium clusters change in ...

Medical research

Calcium channels team up to activate excitable cells

Voltage-gated calcium channels open in unison, rather than independently, to allow calcium ions into and activate excitable cells such as neurons and muscle cells, researchers with UC Davis Health System and the University ...

Medical research

Some sunscreen ingredients may disrupt sperm cell function

Many ultraviolet (UV)-filtering chemicals commonly used in sunscreens interfere with the function of human sperm cells, and some mimic the effect of the female hormone progesterone, a new study finds. Results of the Danish ...

Neuroscience

Researchers discover an epilepsy switch

Scientists at the University of Bonn and the Hebrew University of Jerusalem (Israel) have decoded a central signal cascade associated with epileptic seizures. If the researchers blocked a central switch in epileptic mice, ...

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