Immunology

Second 'don't eat me' signal found on cancer cells

A second biological pathway that signals immune cells not to engulf and kill cancer cells has been identified by researchers at the Stanford University School of Medicine.

Oncology & Cancer

Personalized melanoma vaccines marshal powerful immune response

Personalized melanoma vaccines can be used to marshal a powerful immune response against unique mutations in patients' tumors, according to early data in a first-in-people clinical trial at Washington University School of ...

Oncology & Cancer

B cells linked to immunotherapy for melanoma

Researchers at EMBL's European Bioinformatics Institute and the Medical University of Vienna have found evidence that B cells might play an important role in immunotherapy for melanoma. Currently, immunotherapy is primarily ...

Oncology & Cancer

Researchers probe microbiome-cancer treatment link

Cancer immunotherapies have given patients with particularly intractable cancers new hope, but not everyone benefits. One such immunotherapy, known as CAR T-cell therapy, works only in about a third of the people who take ...

Oncology & Cancer

Genome screen uncovers new targets for cancer immunotherapy

Immunotherapy has revolutionized the treatment of cancer in the last decade, yet many tumors do not respond to these new therapies. A new genome-wide screen of 20,000 human genes in T cells have turned up several new candidates ...

Oncology & Cancer

New lipid signaling target may improve T cell immunotherapy

The immune system surveils our body looking for things that don't belong, often bacteria and viruses. While cancer cells are abnormal cells that undergo unregulated cell growth, they are good at evading detection by the immune ...

Oncology & Cancer

Better tools, better cancer immunotherapy

In the journal Science Immunology, researchers from DTU Health Technology and Jacobs University in Bremen have just published their cutting-edge research demonstrating advancement in detection of a certain type of immune ...

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