Oncology & Cancer

Why don't T cells destroy solid tumors during immunotherapy?

The great hope of cancer immunotherapy is to bolster our own immune cells in specific ways to keep cancer cells from evading our immune system. Although much progress has been made, immunotherapy does not always work well. ...

Oncology & Cancer

Study identifies new therapeutic target for tumor treatment

Northwestern Medicine scientists have identified a new therapeutic target for tumors and developed a compound which slowed tumor growth and bolsters immune responses in mice, according to research published in Science Advances.

Oncology & Cancer

New targets in the fight against pancreatic cancer

Pancreatic cancer remains one of the deadliest malignancies worldwide. Since five-year survival rate for pancreatic ductal adenocarcinoma (PDAC) is only about 3% in patients, PDAC is very difficult to treat with surgery worldwide. ...

Oncology & Cancer

Reconsidering oxygen's role in growth of tumors

Yale researchers have made a discovery that changes conventional thinking about the role that oxygen plays in the growth of tumors—an area of cancer research that has been intensely studied in recent years.

Oncology & Cancer

Obesity is increasing people's risk of cancer. Why?

Obesity is now a global epidemic, and it is increasing people's risk for cancer. The National Cancer Institute lists more than a dozen cancers that are associated with overweight and obesity. But how obesity increases cancer ...

Medications

Study shows promise of new anti-KRAS drug for pancreatic cancer

A small molecule inhibitor that attacks the difficult to target, cancer-causing gene mutation KRAS, found in nearly 30 percent of all human tumors, successfully shrunk tumors or stopped cancer growth in preclinical models ...

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