Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code. New evidence challenges the simplistic ...
Jan 5, 2024
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Medical investigators are theorizing that a combination of two treatments that activate myeloid cells may effectively treat a recalcitrant form of pancreatic cancer that thwarts conventional immunotherapy.
A team of Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind a genetic mutation found in a wide range of cancers, which could serve as a biomarker for improving patient stratification ...
Dec 21, 2023
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Resistance to therapies is one of the obstacles to overcome in cancer treatments. Understanding the mechanisms of this resistance is essential to design strategies that favor tumor cell death. A study led by the Protein Kinases ...
Dec 14, 2023
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Cancer immunotherapy primes a patient's immune system to better find and destroy cancer cells, improving upon the body's natural ability to fight tumors. Contemporary immunotherapy approaches aim to stimulate immune cells ...
Dec 11, 2023
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Immunotherapy using modified chimeric antigen receptor (CAR) T cells has greatly improved survival rates for pediatric patients with relapsed and recurrent leukemia. However, these therapies are not as effective in treating ...
Nov 30, 2023
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The gene-editing technology CRISPR shows early promise as a therapeutic strategy for the aggressive and difficult-to-treat brain cancer known as primary glioblastoma, according to findings of a new study from Gladstone Institutes.
Nov 27, 2023
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Endometrial carcinoma, a cancer of the lining of the uterus, is the most common gynecologic malignancy in developed nations. Over the past decade, its incidence has steadily increased (approximately 1% annually) and mortality ...
Oct 12, 2023
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Researchers at the Department of Chemistry, Scripps Research, California, have discovered how to harness the toxic power of plankton to manufacture anti-cancer molecules.
A new editorial paper titled "DISE, an ancient anti-cancer mechanism that senses mutational load in cancerous cells?" has been published in Oncotarget.
Oct 3, 2023
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