Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways—some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections ...
Mar 12, 2024
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Cancer cells are characterized by their aggressiveness: they grow rapidly and spread to other parts of the body. To enable this, numerous mechanisms come into play, and one of them involves a protein called MYC, which activates ...
Mar 7, 2024
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While better screening and improved treatments are leading to better outcomes for patients with breast cancer, 90% of breast cancer deaths are a result of metastasis, or the cancer growing and spreading to other parts of ...
Mar 6, 2024
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Researchers at Baylor College of Medicine's Dan L Duncan Comprehensive Cancer Center and Human Genome Sequencing Center investigated the extent to which forms of genetic variation called germline or inherited structural variation ...
Mar 4, 2024
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Technological advances in gene sequencing and computing have led to an explosion in the availability of bioinformatic data and processing power, respectively, creating a ripe nexus for artificial intelligence (AI) to design ...
Mar 4, 2024
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The colon is often thought of as one organ, but the right and left parts of the colon have different molecular features in cancers. New research in mice from investigators at the Johns Hopkins Kimmel Cancer Center demonstrates ...
Feb 27, 2024
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A new study identified a set of 140 genes that may help predict enhanced disease-free survival in patients with non-small cell lung cancer (NSCLC) treated with a combination of immunotherapy and low-dose radiation. The results, ...
Feb 23, 2024
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Bladder cancer is one of the more common cancers worldwide. It is considered a major health care problem with a high financial burden. Of these cases, 75% are non-muscle-invasive, which characterizes dangerous diseases with ...
Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes. They also demonstrated ...
Feb 21, 2024
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Researchers at Columbia University have found a molecule that is responsible for arousing dormant cells from breast cancer and nudging them to create metastases. Silencing this molecule, called Malat1, in mice with breast ...
Feb 19, 2024
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