Oncology & Cancer

Protein 'brake' could help develop new cancer treatments

Some cancerous tumors hijack proteins that act as "brakes" on our immune system and use them to form a sort of shield against immune recognition. Immunotherapy treatments have been created that turn off these "brakes" and ...

Oncology & Cancer

Deciphering the male breast cancer genome

Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators. They have conducted the first whole genome sequencing ...

Oncology & Cancer

Review explores therapeutic targets in tumor microenvironment

The tumor microenvironment (TME) is the ecosystem surrounding a tumor, which usually consists of non-tumoral cells and molecules they produce and release. The interplay between tumor cells and the TME significantly impacts ...

Oncology & Cancer

Combining CAR-T cells and inhibitor drugs for high-risk neuroblastoma

Chimeric antigen receptor (CAR)-T cell therapy is a potent emerging weapon against cancer, altering patients' T cells so they can better find and destroy tumor cells. But CAR-T cell therapy doesn't work well in every cancer—including ...

Oncology & Cancer

How early-stage cancer cells hide from the immune system

One of the immune system's primary roles is to detect and kill cells that have acquired cancerous mutations. However, some early-stage cancer cells manage to evade this surveillance and develop into more advanced tumors.

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