Oncology & Cancer

Autophagy genes act as tumor suppressors in ovarian cancer

Shedding light on a decades-old controversy, scientists at the Medical University of South Carolina (MUSC) and University of California at San Diego (UCSD) published findings in PLOS Genetics this month showing that autophagy ...

Oncology & Cancer

Designer probiotic treatment for cancer immunotherapy

Researchers at Columbia Engineering have engineered probiotics to safely deliver immunotherapies within tumors. These include nanobodies against two proven therapeutic targets—PD-L1 and CTLA-4. The drugs are continuously ...

Oncology & Cancer

Cancer cells alter protein production machinery to hasten metastasis

Hormone receptor-positive breast cancer can spread throughout the body via the bloodstream as circulating tumor cells, or CTCs, which eventually reach distal (remote) body sites to form metastatic tumors. An increase in ribosomes, ...

Medical research

Traces of immortality in tumor DNA

To gain an infinite lifespan, cancer cells need to maintain the ends of their chromosomes, known as telomeres. They achieve this in various ways. Scientists from the German Cancer Research Center systematically investigated ...

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