Genetics
Age-related methylation changes in the human sperm epigenome
A new research paper titled "Age-related methylation changes in the human sperm epigenome" has been published in Aging.
Mar 21, 2023
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News tagged with candidate genes
Medical research
Designing a tool for better diagnosis of rare and genetic diseases
Scientists have identified over 10,000 rare diseases with the majority of these diseases being genetic in origin. The vast majority of patients with these diseases experience long and grueling diagnostic odysseys and their ...
Aug 3, 2022
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Neuroscience
Autism-associated protein POGZ controls ESCs and ESC neural induction in brain development
Pogo transposable element derived with ZNF domain (POGZ) is a transcription factor broadly expressed during mouse embryonic development. A high expression level of POGZ in the cortex indicates its important role during brain ...
Jun 24, 2022
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Medical research
Treating neurological symptoms of CHARGE syndrome
CHARGE syndrome is a rare genetic disorder affecting about 1 in 10,000 newborns. It can lead to neurological and behavioral disorders for which no treatment is currently available. Dr. Kessen Patten and his team from the ...
Apr 28, 2021
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Neuroscience
Lab-grown human brain organoids mimic an autism spectrum disorder, help test treatments
Most autism spectrum disorders have a complex, multifactorial genetic component, making it difficult to find specific treatments. Rett syndrome is an exception. Babies born with this form of the disorder have mutations specifically ...
Dec 8, 2020
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Psychology & Psychiatry
Machine learning makes drug repurposing for psychiatric disorders more effective
Artificial intelligence can increase the effectiveness of drug repositioning or repurposing research, according to a study published in Translational Psychiatry. In the study, which was supported by São Paulo Research Foundation—FAPESP, ...
Aug 3, 2020
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Medical research
Gene discovery in fruit flies 'opens new doors' for hearing loss cure in elderly
Scientists at UCL have discovered sets of regulatory genes, which are responsible for maintaining healthy hearing. The finding, made in fruit flies, could potentially lead to treatments for age-related hearing loss (ARHL) ...
Jun 2, 2020
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Vaccination
Researchers advancing novel experimental gene-based COVID-19 vaccine, AAVCOVID
Massachusetts Eye and Ear and Massachusetts General Hospital (MGH), members of Mass General Brigham, today announced progress towards the testing and development of an experimental vaccine called AAVCOVID, a novel gene-based ...
May 5, 2020
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Diseases, Conditions, Syndromes
New process to identify existing drugs for potential COVID-19 treatments
In late January, as the world watched the growing COVID-19 epidemic with increasing unease, a Michigan State University laboratory, which specializes in the use of artificial intelligence and big data to discover therapeutics ...
Apr 13, 2020
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HIV & AIDS
New sequencing study provides insight into HIV vaccine protection
In a new study, scientists led by the U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research identified a transcriptional signature in B cells associated with protection from SIV or HIV infection ...
Aug 28, 2019
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