Medical research

How does HIV get into the cell's center to kickstart infection?

UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications beyond HIV biology.

Diseases, Conditions, Syndromes

A new mechanism by which rotavirus makes you sick

Rotavirus causes gastroenteritis, a condition that includes diarrhea, deficient nutrient absorption and weight loss. Severe cases result in approximately 128,000 deaths annually in infants and children worldwide. Despite ...

Biomedical technology

Reprogramming the shape of virus capsids could advance biomedicine

Bioengineers have found a way to program the size and shape of virus particles by combining viral protein building blocks and templates made from DNA. The resulting nanostructures could have applications in vaccine development ...

Diseases, Conditions, Syndromes

How hepatitis E tricks the immune system

Over 3 million people are infected with the hepatitis E virus every year. So far, no effective treatment is available. An international team has investigated which factors are important for the virus in the course of its ...

Genetics

AAV capsid-promoter interactions in the non-human primate brain

The phenomenon of AAV capsid-promoter interaction recently seen in the rat central nervous system has now been shown to occur in the non-human primate brain. This interaction can directly determine cell-specific transgene ...

Medical research

Researchers describe building blocks of HIV's protective shell

The genome of the HIV-1 virus is protected by a conical-shaped protein shell called a capsid, which performs many functions crucial to viral infection—shielding the virus from the immune system, attaching to cell's transport ...

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