Medical research
Tiny ion is crucial for HIV replication, say chemists
A study by chemists at the University of Chicago has uncovered a new key step in the process that HIV uses to replicate itself.
Jan 24, 2023
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News tagged with capsid
Medications
How a novel drug pushes the HIV capsid to breaking point
Just over a year ago, the European Union and the US Food and Drug Administration approved a new anti-retroviral drug to treat human immunodeficiency virus (HIV) infections. Lenacapavir is the first drug available to patients ...
Feb 13, 2024
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HIV & AIDS
Simulations show how HIV sneaks into the nucleus of the cell
Because viruses have to hijack someone else's cell to replicate, they've gotten very good at it—inventing all sorts of tricks.
Jan 25, 2024
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Medical research
How does HIV get into the cell's center to kickstart infection?
UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications beyond HIV biology.
Jan 24, 2024
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Diseases, Conditions, Syndromes
A new mechanism by which rotavirus makes you sick
Rotavirus causes gastroenteritis, a condition that includes diarrhea, deficient nutrient absorption and weight loss. Severe cases result in approximately 128,000 deaths annually in infants and children worldwide. Despite ...
Dec 11, 2023
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Genetics
New technology is one step closer to targeted gene therapy
Gene therapy is a powerful developing technology that has the potential to address myriad diseases. For example, Huntington's disease, a neurodegenerative disorder, is caused by a mutation in a single gene, and if researchers ...
Dec 9, 2021
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HIV & AIDS
New technique solves HIV capsid structure and could be blueprint of capsid-targeting antivirals
A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors. This work also led to ...
Nov 19, 2021
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Genetics
A new gene-delivery vehicle could make gene therapy for muscle diseases safer and more effective
Genetic muscle diseases lead to progressive muscle wasting and often early death, with few treatment options and no cure. Some gene therapies that use a harmless virus to deliver a functioning copy of a disease-causing gene ...
Sep 9, 2021
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244
Medical research
Altered 'coat' disguises fatal brain virus from neutralizing antibodies
A genetic modification in the 'coat' of a brain infection-causing virus may allow it to escape antibodies, according to Penn State College of Medicine researchers. They say testing people for this and other viral mutations ...
Nov 20, 2020
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HIV & AIDS
HIV up close: Unprecedented view of virus reveals essential steps for causing AIDS
Accomplishing a feat that had been a pipe dream for decades, scientists have recreated in a test tube the first steps of infection by HIV (human immunodeficiency virus), the virus that causes AIDS (acquired immunodeficiency ...
Oct 8, 2020
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