Genetics

Rare congenital heart defect rescued by protease inhibition

A research team at the Greenwood Genetic Center (GGC) has successfully used small molecules to restore normal heart and valve development in an animal model for Mucolipidosis II (ML II), a rare genetic disorder. Progressive ...

Cardiology

Scientists identify key factor regulating abnormal heart growth

The human heart is like a sponge, able to expand and grow, increasing its capacity to take up blood. In theory, an enlarged heart can also squeeze out more blood, with more power, than an average-sized heart. But in reality, ...

Cardiology

Modulating copper levels in the treatment of heart disease

An article published in Experimental Biology and Medicine provides new insights regarding the use of trientine (TETA), a copper chelator traditionally used to treat copper overload conditions such as Wilson's disease, in ...

Cardiology

Three landmark heart studies shed light on sudden cardiac arrest

Today, at the American Heart Association Scientific Sessions, the research group led by Sumeet Chugh, MD, professor of Medicine and associate director of the Smidt Heart Institute, presented three critical research studies ...

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