A new study assesses the effect of the gremlin-1 (GREM1) protein on the in vitro and in vivo stability of bone marrow stem cell (BMSC)-derived cartilage engineered within scaffolds. The study design and results are reported ...
Apr 28, 2022
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Repair of cartilage injuries or defects is aided by the introduction of mesenchymal stem cells (MSCs), which can be incorporated into hydrogels to amplify their effects. In a new report, researchers directly compared chondrogenic ...
May 9, 2019
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During cartilage development, chondrocytes secrete the extracellular matrix (ECM) and embed within the same environment. During progressive joint disease, such as osteoarthritis (OA), dysregulation of the process can lead ...
Highly specialized cartilage is characteristically avascular and non-neural in composition with low cell numbers in an aliphatic environment. Despite its apparent simplicity, bioengineering regenerative hyaline cartilage ...
Rhode Island Hospital researchers have found that the absence of the Shp-2 enzyme near specialized cartilage cells can lead to the development of multiple benign cartilage tumors in mice, a model that recapitulates the rare ...
Jul 18, 2013
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Researchers from the RIKEN Center for Integrative Medical Sciences in Japan have identified the first gene to be associated with adolescent idiopathic scoliosis (also called AIS) across Asian and Caucasian populations. The ...
May 12, 2013
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(Medical Xpress)—New research has shown that it is possible to grow new bone by "nanokicking" stem cells 1,000 times per second using high frequency vibrations.
Apr 5, 2013
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Osteoarthritis is a progressive joint disease that affects approximately one third of individuals age 65 and older. The disorder causes gradual loss of joint cartilage and bony degeneration while simultaneously creating new ...
Feb 5, 2013
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