Medical research

Defense against joint degeneration

During cartilage development, chondrocytes secrete the extracellular matrix (ECM) and embed within the same environment. During progressive joint disease, such as osteoarthritis (OA), dysregulation of the process can lead ...

Medical research

3-D bioPen: A hydrogel injection to regenerate cartilage

Highly specialized cartilage is characteristically avascular and non-neural in composition with low cell numbers in an aliphatic environment. Despite its apparent simplicity, bioengineering regenerative hyaline cartilage ...

Genetics

Gene associated with adolescent idiopathic scoliosis identified

Researchers from the RIKEN Center for Integrative Medical Sciences in Japan have identified the first gene to be associated with adolescent idiopathic scoliosis (also called AIS) across Asian and Caucasian populations. The ...

Diseases, Conditions, Syndromes

Nonsurgical treatment of osteoarthritis discussed

Osteoarthritis is a progressive joint disease that affects approximately one third of individuals age 65 and older. The disorder causes gradual loss of joint cartilage and bony degeneration while simultaneously creating new ...