Immunology

Novel genomic tools provide new insight into human immune system

When the body is under attack from pathogens, the immune system marshals a diverse collection of immune cells to work together in a tightly orchestrated process and defend the host against the intruders. For many decades, ...

Genetics

CRISPR screening identifies potential HIV treatment targets

Investigators from Whitehead Institute, the Ragon Institute of MGH, MIT and Harvard and the Broad Institute of MIT and Harvard have used CRISPR-Cas9 gene-editing technology to identify three promising new targets for treatment ...

Immunology

Scientists tackle two distinct immunological disorders

In two recent studies, a team of scientists reports the mechanisms underlying two distinct immunological disorders affecting children and adults. Stephanie Humblet-Baron (VIB-KU Leuven) was the researcher at the helm of both ...

HIV & AIDS

HIV latency differs across tissues in the body

Mechanisms that govern HIV transcription and latency differ in the gut and blood, according to a study published November 15 in the open-access journal PLOS Pathogens by Steven Yukl of San Francisco Veterans Affairs Medical ...

Immunology

How chronic infections can outsmart the immune system

Professor Simona Stäger and her team at INRS have discovered a mechanism that causes the body to sabotage its own defenses against infection by visceral leishmaniasis, a fatal tropical disease. This discovery could help ...

Immunology

Study finds potential key to immune suppression in cancer

In a study investigating immune response in cancer, researchers from Moffitt Cancer Center in Tampa, Fla., and the University of South Florida have found that interaction between the immune system's antigen-specific CD4 T ...

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