Metastatic cells occur in many forms of cancer. They originate in primary tumors and then break away and migrate. They travel through the tissues surrounding them, through blood vessels or lymphatic channels. Along the way, ...
Mar 8, 2022
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The enzyme caspase-8 induces a molecular cell death programme called pyroptosis without involving its enzymatic activity, a new study by Hamid Kashkar published in Nature shows. In order to safeguard healthy and functioning ...
Nov 26, 2019
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Cancer cells are characterised by the ability to evade apoptosis, a type of programmed cell death that allows the organism to remove damaged cells. Many studies devoted to new chemotherapy treatments aim to induce apoptosis ...
Apr 17, 2019
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Cell death is an important aspect of tissue homeostasis, as well as inflammation and disease pathogenesis related to infection, injury, and tumor growth. Tumor necrosis factor-α (TNFα) coordinates cell death in a variety ...
Jan 17, 2019
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Leuven researchers led by professor Bart De Strooper (VIB-KU Leuven) have identified a new role for PARL, a protein linked to Parkinson's disease. In this week's edition of the Proceedings of the National Academy of Science, ...
Jan 3, 2019
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Scientists from the VIB-UGent Center for Inflammation Research identified the mechanisms by which the bacterial pathogen Clostridium difficile kills intestinal epithelial cells (IECs), thus destroying the protective mucosal ...
Nov 21, 2018
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A highly detailed study of how the roundworm C. elegans forms oocytes suggests that the egg-making process leads to the formation and subsequent destruction of cells with an extra nucleus, but that some cellular materials ...
Jul 19, 2018
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Structural biologists at St. Jude Children's Research Hospital have discovered how a key protein functions to trigger cell's suicide machinery, called apoptosis. The scientists found that the protein, called BOK, is controlled ...
May 17, 2018
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Scientists at the University of Glasgow have discovered a process to trigger the death of cancer cells that could be more effective than current methods.
Aug 29, 2017
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New study results show for the first time how dying cells ensure that they will be replaced, and suggests an ingenious, related new approach to shrinking cancerous tumors. A research team from Rush University Medical Center ...
Jun 19, 2017
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