In people with Alzheimer's disease (AD), the epigenetic regulator HDAC6 (histone deacetylase 6), which controls many biological processes, is significantly overexpressed in the brain.
Nov 27, 2023
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A team at the Medical University of South Carolina and Cincinnati Children's has developed a sophisticated model for studying the diseased colon that could lead to the development of personalized treatments for colon-related ...
Nov 20, 2023
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Investigators from the UCLA Health Jonsson Comprehensive Cancer Center have developed an artificial intelligence (AI) model based on epigenetic factors that is able to predict patient outcomes successfully across multiple ...
Nov 16, 2023
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An international team of scientists has uncovered the vital role of microglia, the immune cells in the brain that acts as its dedicated defense team, in early human brain development. By incorporating microglia into lab-grown ...
Nov 15, 2023
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UCLA researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream—potentially revealing a new pathway ...
Nov 9, 2023
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In 2021, a Northwestern University-led research team began working to develop an implantable "living pharmacy" to control the human body's sleep/wake cycles. Now, the researchers have completed a major step toward achieving ...
Nov 9, 2023
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Cancer cells are often a mess of mutations. About 20% to 25% of cancers involve mutations in a complex of molecules called SWI/SNF. Yet drugs designed to block SWI/SNF activity haven't always worked as expected. Researchers ...
Nov 3, 2023
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Atherosclerosis is considered a frequent cause of cardiovascular diseases and strokes. Despite medical progress, case numbers are constantly rising. Targeted new therapeutic approaches are therefore more important than ever.
Nov 2, 2023
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Researchers at MUSC Hollings Cancer Center believe that some drugs already approved by the FDA or currently in clinical trials could be repurposed for certain breast cancer patients whose cancer has become resistant to standard ...
Nov 2, 2023
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Cancer cells are notorious for rapidly changing their phenotype, driving within-host spread and evading treatment. Scientists in Plön have used a mathematical model to understand the role of a signal used by cancer cells ...
Oct 26, 2023
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