Immunology

Molecular component of caffeine may play a role in gut health

Brigham researchers studying how and why certain cell types proliferate in the gut found that xanthine, which is found in coffee, tea and chocolate, may play a role in Th17 differentiation. Insights may help investigators ...

Immunology

Researchers reveal metabolic processes key to lung repair

Scientists at the Francis Crick Institute have uncovered how cells lining the lung airways change their metabolism, and how this process is key to helping the lungs heal after infection or damage.

Oncology & Cancer

New insights into the genetic basis of leukemia

Acute myeloid leukemia (AML) is a malignant disease of the hematopoietic system that originates from immature precursors of red blood cells, platelets and part of the white blood cells. While in healthy people the multiplication ...

Medical research

RXR, the cell protein that keeps blood stem cells young and fit

The cell protein retinoid X receptor (RXR) is a key factor in the maintenance of hematopoietic stem cells, the immature stem cells that give rise to all the blood cell lineages. RXR ensures that these cells remain youthful ...

Immunology

How tiny changes help T cells to survive

The research group led by immunologists Vigo Heissmeyer and Taku Ito-Kureha of LMU and Helmholtz Munich has revealed the essential function of m6A modifications in T cells.

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