The fusion of two adjacent genes can cause cancer by kicking mitochondria into overdrive and increasing the amount of fuel available for rampant cell growth, researchers at Columbia University Medical Center (CUMC) have discovered. ...
Jan 3, 2018
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Researchers at Charité's NeuroCure Cluster of Excellence have successfully identified the mechanism behind rapid signal transmission. Their work, published in the current issue of Nature Neuroscience, shows that bridging ...
Dec 14, 2017
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(HealthDay)—The fibroblast growth factor receptor 3 (FGFR3) transforming acidic coiled-coil containing protein 3 (TACC3) (FT3) gene fusion recruits endogenous TACC3 away from the mitotic spindle, resulting in errors in ...
Sep 18, 2017
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A study by the University of Warwick sheds new light on gene fusion in bladder and brain cancer.
Aug 30, 2017
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Genetic mutations caused by rearranged chromosomes drive the development and growth of certain colorectal cancers, according to new research conducted by Weill Cornell Medicine investigators.
Jul 12, 2017
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A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues. A study published June 1 by Nature ...
Jun 1, 2017
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A team of scientists has demonstrated the mechanism by which ETO2-GLIS2, a gene fusion, promotes the development of an aggressive form of pediatric leukemia. The findings, published in Cancer Cell, also reveal an opportunity ...
May 9, 2017
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A novel gene therapy using CRISPR genome editing technology effectively targets cancer-causing "fusion genes" and improves survival in mouse models of aggressive liver and prostate cancers, University of Pittsburgh School ...
May 1, 2017
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Details of a pioneering IVF technique using mitochondrial replacement therapy (MRT) have been revealed, giving hope to those families with inheritable mitochondrial disorders that they may be able to have healthy children ...
Apr 3, 2017
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New research suggests a novel strategy to target a genetic anomaly that occurs in half of all prostate cancers.
Mar 23, 2017
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