Canadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components interacts with the cell membrane.
Diabetes is a condition in which the body produces too little or no insulin. Diabetics thus depend on an external supply of this hormone via injection or pump.
Aug 23, 2023
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Premature rupture of the amniotic sac can have devastating consequences, but scientists in Japan are studying instances when the damaged sac repairs itself—a phenomenon that requires cooperation of the developing fetus.
For cancer cells to metastasize, they must first break free of a tumor's own defenses. Most tumors are sheathed in a protective "basement" membrane—a thin, pliable film that holds cancer cells in place as they grow and ...
Mar 8, 2021
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For many inherited diseases, such as cystic fibrosis or Huntington disease, the disease-causing genetic mutation damages or removes a protein that has an essential role in the body. This protein defect is the root cause of ...
Aug 8, 2013
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(Medical Xpress)—To move material in bulk, the standard shipping container used by cells, is the vesicle. These approximately 40-micron sized spheres are essentially recyclable grocery bags that can be loaded and adorned ...
(Medical Xpress)—The blood-brain barrier (BBB) prevents most large or hydrophilic (polar) molecules from getting into the brain. For many neurological diseases, like Parkinson's, the presence of the BBB severely limits ...
(Medical Xpress)—Membrane fusion is a highly regulated event, both inside cells, and between them. From the moment a sperm first fuses with an egg, subsequent developmental events depend upon its proper control. Inside ...
Researchers have published the first highly detailed description of how neurotensin, a neuropeptide hormone which modulates nerve cell activity in the brain, interacts with its receptor. Their results suggest that neuropeptide ...
Oct 10, 2012
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A University of Wisconsin-Madison research team has solved a 25-year mystery that may lead to better treatments for people with learning deficits and mental retardation.
Jun 8, 2011
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The cell membrane (also called the plasma membrane or plasmalemma) is the biological membrane separating the interior of a cell from the outside environment.
It is a semipermeable lipid bilayer found in all cells. It contains a wide variety of biological molecules, primarily proteins and lipids, which are involved in a vast array of cellular processes such as cell adhesion, ion channel conductance and cell signaling. The plasma membrane also serves as the attachment point for both the intracellular cytoskeleton and, if present, the extracellular cell wall.
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