A study has found that a mitochondrial disease in newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely. The finding is a significant step forward in understanding the syndrome and ...
May 3, 2023
0
120
Metabolic disorders play a central role in many common conditions, including Alzheimer's, depression, diabetes and cancer, which call for reliable as well as non-invasive diagnostic procedures. Until now, radioactive substances ...
Apr 28, 2023
0
182
Pancreatic cancers are deadly and hard to treat, in part because they are so often detected at an advanced stage; overall five-year survival rates are about 11%. Two separate labs at Boston Children's Hospital took out-of-the-box ...
Apr 25, 2023
0
53
Many cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medications. This is the case, for example, with alpelisib, a drug that has been approved for ...
Apr 11, 2023
0
65
New research suggests a strategy to ward off age-related weight gain, which could prevent obesity and associated health disorders like type 2 diabetes, heart disease and chronic inflammation.
Apr 6, 2023
0
61
A key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now shown that with this ...
Apr 6, 2023
0
51
Cells contain diverse populations of molecules called lipids, which are organic fatty compounds. Lipid metabolism, the synthesis and breakdown of these lipids, plays a key role in regulating the composition and functions ...
Mar 30, 2023
0
38
Scientists from the Trinity Biomedical Sciences Institute (TBSI) have shed new light on aging processes in the brain. By linking the increased presence of specialized immune cells to conditions such as Alzheimer's disease ...
Mar 8, 2023
0
203
Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence to proliferation is still poorly understood. ...
Mar 1, 2023
0
790
New research from the University of Michigan Rogel Cancer Center reveals that the metabolic pathways that make a specific type of T cell function are different than previously believed. The key to this discovery lies in a ...
Feb 18, 2023
0
96
