Medical research

How a microRNA protects vascular integrity

Short RNA molecules known as microRNAs (miRNAs) play a vital role in the regulation of gene expression. Anomalies in miRNAs expression and function have been implicated in pathological processes, such as the development of ...

Medical research

The difference between physical and psychosocial stress

A sports stress test and psychosocial stress produce similar stress hormone increases. And yet, the first one is perceived as positive, the second one as negative. Researchers attempt to find out why.

Genetics

A deep dive into cellular aging

Scientists at Sanford Burnham Prebys Medical Discovery Institute and Harvard University have discovered that mitochondria trigger senescence, the sleep-like state of aged cells, through communication with the cell's nucleus—and ...

Oncology & Cancer

Disorderly DNA helps cancer cells evade treatment

Each cell in the human body holds a full two meters of DNA. In order for that DNA to fit into the cell nucleus—a cozy space just one hundredth of a millimeter of space—it needs to be packed extremely tight.

Oncology & Cancer

Researchers identify new therapeutic target for colorectal cancer

Researchers at the University of Toronto have identified a key protein that supports the growth of many colorectal cancers. The study, which will be published December 27 in the Journal of Cell Biology, reveals that a protein ...

Oncology & Cancer

New principle for activation of cancer genes discovered

Researchers have long known that some genes can cause cancer when overactive, but exactly what happens inside the cell nucleus when the cancer grows has so far remained enigmatic. Now, researchers at Karolinska Institutet ...

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