Oncology & Cancer

Scientists 'get on the nerves' of cancer cells

Modulation of neuroreceptors can stop the growth of lung carcinoma (cancer) cells, according to a recent study conducted by a group of researchers from the Institute of Bioorganic Chemistry of the Russian Academy of Sciences ...

Diseases, Conditions, Syndromes

New window on fibrosis

DDR1 is a receptor tyrosine kinase (RTK)—a cell surface receptor—that regulates multiple functions including the maintenance of the normal structure of tissues, but which also contributes to pathological conditions including ...

Medications

Ketamine isn't an opioid and treats depression in a unique way

Ketamine has gotten a bad rap as an opioid when there's plenty of evidence suggesting it isn't one, Johns Hopkins experts say. They believe this reputation may hamper patients from getting necessary treatment for the kinds ...

Obstetrics & gynaecology

Scientists find clue to 'maternal instinct'

Oxytocin is widely referred to as the love hormone and plays an important role in the regulation of social and maternal behavior. In recent years, the oxytocin system in the brain has received tremendous attention as key ...

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Receptor (biochemistry)

In biochemistry, a receptor is a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a "ligand," and may be a peptide (such as a neurotransmitter), a hormone, a pharmaceutical drug, or a toxin, and when such binding occurs, the receptor undergoes a conformational change which ordinarily initiates a cellular response. However, some ligands merely block receptors without inducing any response (e.g. antagonists). Ligand-induced changes in receptors result in physiological changes which constitute the biological activity of the ligands.

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